Explore the latest thought leadership from Credence MedSystems on injectable drug delivery challenges, evolving therapy requirements, device and user considerations, and pharmaceutical manufacturing.
A promising injectable therapy can clear its safety and efficacy hurdles and still stall on a question that often arrives too late: how will it actually be delivered? When a molecule cannot remain stable in liquid form, or when two drug components cannot be co-formulated, the delivery strategy becomes critical. A lyophilized product may need […]
Emerging biopharma companies originated 65% of new active medicines launched worldwide from 2020 to 2024, and filed for nearly half of U.S. launches in that period.1 Larger pharmaceutical companies often make that decision within the boundaries of what they already have: legacy device platforms, established supplier relationships, existing assembly lines and internal device teams built […]
Pharmaceutical pipelines are creating growing demand for larger-volume injectable drug delivery. By accommodating greater delivery volumes, 3 mL and 5 mL prefilled syringes can provide greater flexibility in formulation and dose delivery and may reduce the need for higher drug concentrations or multiple injections. Moving to a larger-volume prefilled syringe has implications beyond drug capacity. […]
Intravitreal biologics and other therapies have transformed the treatment of retinal disease, but they have also concentrated significant clinical stakes into a single, sub-100-microliter injection. Unlike a subcutaneous or intramuscular dose, an intravitreal injection is delivered directly into a small, delicate, and largely incompressible compartment of the eye, where even small variability in delivered volume, […]